Lumbar total disc replacement: it still needs further follow-up?
In a recent article in Spine, Guyer et al. reported on the results of a 5-year follow-up results on a prospective, randomized trial comparing two kinds of lumbar total disc replacement (TDR): Charite [metal-on-polyethylene (MoP) TDR, the control] vs. Kineflex-L [metal-on-metal (MoM) TDR, the investigational]. To the best of my knowledge, there are few clinical comparison studies between two different artificial discs in the lumbar spine. The present study might be one of the few TDR clinical trials carried out in over 15 years in the U.S. These trials serially report comparison results between an investigational prosthesis and the control at certain time periods of follow-up. The authors had already published the 2-year follow-up results of the comparison study with the identical implants and in identical specimens as an early outcome with those of the present study (1).